Probably not. I mean, the flaws of the game were pretty well identified by previous designers and the fanbase. Also, considering how vilified WoW and Diablo were in relation to the product and the further fact that there's not been really any other Hot New Game to ape, I do have some serious hope that they'll focus on the TTRPGs strengths.
Then again, Mike Mearls is leading the team. But, eh, he can't be much worse than Collins or Slavicsek. In the end, it depends on how much serious playtesting the whole game gets. Even 4E D&D could've been saved from the crap pile with some proper playtesting.
You already know what mechanics I hope for. As for what mechanics I expect, that's a more complicated question. But I have been trolling the 4E D&D boards and listened to some complaints, so here's a list of things I expect that they will get around to in the game in no particular order.
[*] They will have a lot more skills in the game. Monte Cook loves pontificating about skills and some of the strongest '4E D&D is WoW!' are in reference to the neutered skill system.
[*] Attributes become even more pointless than they already are. Good.
[*] They either switch to full-on random/DM fiat magical items with a tiny token variety you can buy like they tried to do in Essentials or magical items become a min-max paradise where players get exactly what they want whenever they want with the only restrictions being item amount and level. My money is on the latter, because that sells more books, but I have real hope that Monte Cook will do the former; though hopefully there won't be bullshit they had last time where there was such a thing as +6 swords for sale, even if they're 'common'.
[*] Minions are definitely staying in. I hate them as a mechanic because they smack of laziness, but in almost all 4E D&D games I've run the players loved the fucking shit out of them.
[*] Characters are probably going to be as overcomplicated as they are now. Meaning, a 1st level character will have their choice of race, class, background, feats, theme, powers, and skills. Gotta move product somehow.
[*] 5E D&D mechanics will definitely hype up the more action-oriented gameplay. I don't exactly see how they will actually do that since people have an unwarranted aversion to Save-or-Sucks and no one seems smart enough to realize that Save-or-Sucks work better without critical existence failure. I mean, even Mutants and Masterminds d20 got that one right.
[*] 5E D&D will have more classes at the outset than 4E D&D. Going to market without a druid, monk, and barbarian really effed them in the A.
[*] 5E D&D will have a more workable and less punitive multiclassing system of some sort. Expect hybrid classing to be in the basic book even.
[*] Expect rituals to either be really boosted in effect or usability or be taken out of the game entirely. If the latter happens, the probability of it being recycled back into character's utility powers or, god forbid, giving combat effects a non-utility function is really goddamn low.
[*] The classes in the core book will have a variety to them about as diverse as the classes offered in 4E D&D near the tail end of the lifespan. Meaning that the spread will be more like 4E Battlemind / Wizard / Scout / Warlord / Original Assassin / Runepriest / Paladin / Monk / Slayer / Cleric in terms of inter-class diversity.
[*] The role system is staying in. It will probably be better defined and have different names to it, though. Instead of something like Striker / Defender / Leader / Controller it'll probably something that has a less MMORPG-ish visceral reaction like Protector / Mastermind / Assaulter / etc.
[*] Martial classes get knocked firmly the fuck back to Conan tier. However, because balance will be the huge thing, the other classes will be brought down to Conan tier either explicitly or with some kind of cognitive dissonance shellgame that 4E D&D did.
[*] 5E D&D will not have anything resembling a decent default campaign setting. Mike Mearls has punted on the issue every chance he gets because he is a stupid fuckstick who doesn't realize that a decent campaign setting is
the thing to ensure loyalty and smooth over ruffled feathers. Expect either a rehash of something that was already detailed like Eberron or Forgotten Realms or some retarded 'points of light' crap that will be no more detailed than Ninter
Fail Vale if they even bother.
Basically, I expect to see 5E D&D be 4.5E D&D with some facepaint. As in, all of the fixes internal to 4E D&D they should have had at the outset (such as a better magical item and skill challenge system) will still be in the game. I very much doubt that 5E D&D will look more like 3E D&D because of Pathfinder and also the fact that fixing 3E D&D would take much more effort than fixing 4E D&D. Well, fixing as in having something that will appeal to casual gamers, not the best TTRPG that there can be. I also strongly doubt that 5E D&D will be a totally new system either. Unless they have a design team much larger than what they officially put out they won't have the time to create and playtest something from scratch.
Unless... unless Mearls was working on 5E D&D for a long time before the announcement.